Acute decline in kidney function in people with acute liver disease or an exacerbation of end-stage liver disease is called hepatorenal syndrome (HCGT). The disease is mainly seen in patients with cirrhosis, ascites, portal hypertension, alcoholic hepatitis, or more rarely, liver tumors, fulminant hepatitis due to different causes.

Hepato-renal syndrome (HPS) occurs mainly in patients with advanced cirrhosis, but can also be seen in acute liver failure. HRS can appear spontaneously. The mortality rate of patients with hepatorenal syndrome is about 80-95%. Median survival is 2 weeks.

The main treatment methods for hepatorenal syndrome are the use of vasopressors, albumin and some invasive techniques, the aim is to prolong the patient's life time.

Organ transplantation in general and liver transplantation in particular is one of the greatest scientific achievements in medicine. Liver transplantation is the best treatment for end-stage liver diseases such as liver cancer, decompensated cirrhosis or liver failure. The world's first liver transplant was performed in the United States in 1963. In Vietnam, the first liver transplant was performed in 2004.

Acute renal failure is a dangerous disease. There are many causes of acute renal failure. These causes are divided into: Pre-renal causes of acute renal failure, intra-renal causes of renal failure, and post-renal causes of renal failure.

Leptospira is an acute infectious disease caused by the spirochete Leptospira. The disease can be found in many countries around the world. The disease is transmitted from animals to humans, through the skin and mucous membranes. Leptospira disease is characterized by systemic toxic septicemia syndrome and hepatorenal syndrome.

Acute renal failure is mainly caused by age, the older you are, the higher the risk of acute renal failure. Acute renal failure has a high probability of leading to death. Therefore, early diagnosis, detection of the disease as well as proper treatment play a very important role.