Helicobacter pylori (H. pylori) is an important cause of peptic ulcer disease and gastric malignancies. The treatment of H. pylori remains a challenge, because many factors determine the success of therapy such as resistance to primary or secondary antibiotics, drug concentrations on the mucosa, patient compliance, side effects and costs.

Over the past 4 decades, the problem of researching Helicobacter pylori (H. pylori) bacteria has occupied the minds of many scientists around the world. H. pylori is a bacteria commonly found in patients with chronic gastritis, peptic ulcer disease (peptic ulcer disease) and stomach cancer (stomach cancer), as well as in patients with chronic gastritis. as in healthy people.