Cystic fibrosis (CF) is a life-limiting condition that most commonly affects Caucasians. Defects in the cystic fibrosis transmembrane conductance regulatory protein affect chloride and bicarbonate secretion, as well as dysregulation of the epithelial sodium channel (ENaC). These changes result in impaired mucociliary clearance, reduced airway surface mucus, and an exaggerated proinflammatory response to infection.

Cystic fibrosis can cause infections, poor absorption of nutrients, and it can also affect the sweat glands along with the male reproductive system. In addition to blood tests and sweat tests, to accurately diagnose the disease, your doctor may request to evaluate the condition of the disease with imaging tests such as: chest X-ray, chest or abdominal CT scan, chest or abdominal MRI, abdominal ultrasound or sinus CT