Rhabdomyolysis is a syndrome in which skeletal muscle cells are damaged and destroyed, leading to the release of substances in muscle cells into the blood such as potassium, uric acid, lactic acid, myoglobin or enzymes that disrupt electrolytes, metabolic acidosis and even cause acute kidney failure.

Continuous venovenous hemofiltration (CVVH) is a blood filtration technique that allows continuous (> 12 hours) removal of water and solutes with a molecular weight of less than 50,000 daltons from the patient's blood. In particular, with a large volume of replacement fluid (≥ 35ml/kg/hour) through a convection mechanism, it helps to effectively remove solutes with an average molecular weight similar to that of pro-inflammatory substances.