Uses of Vesanoid

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1. Mechanism of action of the drug Vesanoid

Vesanoid medicine contains tretinoin - a retinoid of the vitamin A group. Drugs can control normal cell growth, cell differentiation and induce cell death. In APML, cells are trapped in an immature form, rendering the immature cell's replica line inoperable. The compound tretinoin also makes young cells inactive and mature, thereby slowing or stopping the growth of cancer cells.

2. Indications for the use of Vesanoid

Vesanoid drugs are indicated to kill cancer cells by interfering with the growth and reproduction of cancer cells. Medicines can be used to treat certain leukemias, such as leukemia, or acute leukemia.

3. Dosage and usage of Vesanoid

The recommended adult dosage is usually 45mg/day and taken once a day. However, the patient should use the drug as prescribed by the doctor to achieve the optimal effect for the treatment process.
Vesanoid is used in capsule form and by mouth. When taking the drug, the patient should pay attention to swallow the whole pill to be effective, avoid chewing, or breaking or crushing the medicine before taking it. Patients can take Vesanoid with or without food.
In addition, Vesanoid drugs also work to treat acne.
When using Vesanoid, patients should not add vitamin A because there may be drug interactions that reduce the effectiveness of the drug in treatment.
Note: The above recommended therapeutic dose for Vesanoid is for reference only. Therefore, patients should consult a doctor before using them.
If the patient using Vesanoid forgets a dose, use the missed dose as soon as he remembers. However, if the interval between the missed dose of Vesanoid and the next dose is close, it is possible to skip the missed dose and take the next dose. Patients should also note that it is not recommended to double the dose of Vesanoid, because it can cause drug overdose and unwanted side effects that affect the patient's current health during treatment with Vesanoid. Vesanoid drugs.
In case the patient accidentally takes Vesanoid drug in excess of the prescribed amount and has some signs of unwanted side effects, it is necessary to take the patient to the nearest medical facility to receive emergency treatment. get medical help promptly and help avoid serious side effects.

4. Unwanted side effects and some notes on using Vesanoid drugs

Using Vesanoid during treatment may experience some unwanted side effects. Depending on the specific case, there will be different levels of reaction. When experiencing symptoms causing side effects, patients should talk to medical staff for timely medical support.
Headache and Musculoskeletal Pain: Headache is one of the common side effects of Vesanoid. This symptom usually occurs within a few hours of use. Your doctor may prescribe over-the-counter medications to treat headaches during treatment. Headaches tend to occur around the time of taking the medication or go away before the next dose. If the pain persists or is severe, the patient should notify the doctor for immediate assistance. Patients are always in a state of fatigue: After cancer treatment, patients always feel exhausted and tired, and this condition takes a long time to improve. Therefore, patients need to be guided to adjust as well as plan a long rest to save energy for important activities. In addition, exercise can be done to improve fatigue by walking, relaxing... Flu-like symptoms. Patients may experience muscle aches, fever, chills, and fatigue. Increased Cholesterol and Triglycerides: Vesanoid may cause a temporary increase in cholesterol and triglyceride levels and triglycerides. Therefore, when using Vesanoid, patients need to monitor the levels of these indicators. Hepatotoxicity: Vesanoid can cause hepatotoxicity and liver function tests should be performed to control this condition. When the patient experiences symptoms such as yellow skin and eyes, dark brown urine, abdominal pain... are all signs of liver toxicity that the patient should pay attention to. Bleeding or bleeding. Vesanoid can cause serious bleeding in some special cases. If the patient has bruises or excessive bleeding with nosebleeds, bleeding gums, etc., blood tests should be performed to detect abnormalities early. Nausea and vomiting can occur with the use of the drug: Patients can tell their doctor to prescribe medication to help control nausea or vomiting. In addition, the doctor will also prescribe appropriate dietary changes to improve the current medical condition. For example, the patient should avoid using foods that can aggravate these symptoms such as foods high in fat, fat or sour spices.... Peripheral edema. Peripheral swelling due to fluid retention in the extremities occurs with the use of Monjuvi. The patient may have swelling of the hands, arms, feet, ankles, etc. The swelling causes the patient to feel uncomfortable. Rash. Some patients may experience a rash, itchy red bumps. Therefore, an alcohol-free moisturizer can be used to apply. In case the skin is bleeding or cracked, it should be cleaned before applying the cream Increase the number of white blood cells. Vesanoid can cause leukocytosis. This condition is very difficult to detect. However, patients need to regularly monitor the number of white blood cells in the blood. If the patient experiences this condition, the drug should be discontinued. Mucositis: Some cancer treatments can cause ulcers or pain in the mouth and throat. If the patient experiences signs of pain in the tongue, mouth, and throat, notify the doctor so that they can help improve the inflammation. Patients should limit the use of alcoholic water, should only rinse their mouth with salt water diluted with warm water, use a soft toothbrush, should drink a lot of water to avoid too dry mouth... Differential syndrome . This condition may be caused by tretinoin-induced changes in blood cell production in patients with blood cancers. Symptoms of this syndrome include fever, sudden weight gain, swelling, low blood pressure, bone pain... The syndrome can be treated with high doses of IV steroids after 7 to 12 days of using Vesanoid. Heart related problems. Vesanoid may cause an irregular heartbeat with symptoms of dizziness or fainting. At the same time, Vesanoid drugs also cause changes in blood pressure of patients. Therefore, it is necessary to monitor these indicators during treatment with Vesanoid. Vesanoid medicine contains tretinoin ingredient which belongs to the group of anti-parasitic, anti-viral, anti-fungal drugs. The drug is indicated in the treatment of controlling and slowing the growth of cancer cells.
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Reference source: oncolink.org