Uses of Asumalife

This is an automatically translated article.

1. What is Asumalife?

What is Asumalife? On the market, Asumalife is produced in two main forms: tablets and syrup mixtures (for children). However, this article only mentions Asumalife tablets, which are more commonly used in Vietnam.
Asumalife is prepared under tablets with the main ingredients including:
Active ingredient: Ketotifen (Ketotifen fumarate) content of 1 mg. Excipients : Just enough 1 tablet 1 mg. Ketotifen fumarate is an active ingredient that selectively inhibits histamine H1 receptors, and is also a mast cell protector.
Ketotifen fumarate acts mainly on the respiratory system, so it should be used as a medicine to treat bronchial asthma. However, Ketotifen has no effect on acute asthma attacks because it does not dilate the bronchi, but only has an anti-allergic effect through inhibiting the release of allergenic chemical mediators from the cells. Mast and inflammatory mediators such as Histamine, Leukotriene C4 and D4 (SRS - A) and PAF. Specifically, Ketotifen fumarate inhibits histamine H1 receptors and Phosphodiesterase at the same time, thereby increasing the content of cAMP in Mast cells, inhibiting PAF-induced platelet activation, and preventing Eosinophil aggregation. inflammatory sites.

2. What are the effects of Asumalife?

Asumalife is indicated for treatment in the following cases:
Prevention of symptoms in bronchial asthma, allergic bronchitis. Combination treatment with basic asthma-specific drugs. Patient has chronic urticaria of unknown cause. Allergic conjunctivitis. Allergic rhinitis . Allergic dermatitis. Food allergies, pollen. Side effects of antihistamines. However, in the following cases, Asumalife is not allowed to be prescribed:
Hypersensitivity to any of the ingredients of Asumalife. History of allergy to other drugs containing the active ingredient Ketotifen fumarate. History of allergy to other antihistamines. Women who are pregnant in the first 3 months or women who are breastfeeding. The patient has a history of or is currently experiencing seizures or convulsions.

3. Dosage and usage of Asumalife

Dosage
Adults
Initial dose (3 - 4 days first): Take 1 tablet (1 mg)/time x 1 time/day in the evening meal. Next day dose: Take 1 tablet (1 mg)/time x 2 times/day. Take the medicine at breakfast and dinner. Increase dose: Take 2 tablets (2 mg) / time x 2 times / day. Take the medicine at breakfast and dinner. Children
Children ≥ 3 years old: Take 1 tablet (1 mg)/time x 2 times/day. Take the medicine at breakfast and dinner. Children 6 months to under 3 years: Tablets are not recommended. Syrup should be used for oral administration, dose 0.5 mg x 2 times/day. Children < 6 months: Not recommended.

4. Side effects encountered when using Asumalife

The use of Asumalife in high doses or for a long time can cause side effects such as:
Common: Drowsiness to deep sleep, fatigue, dizziness, dizziness. Uncommon: CNS symptoms of excitability, insomnia, temper, irritability. Rare: Blood abnormalities such as leukopenia, agranulocytosis, hemolytic anemia, thrombocytopenia. Frequency unknown: Cardiovascular symptoms such as palpitations, arrhythmia. Skin symptoms such as skin rash, urticaria, Stevens Johnson syndrome, erythema multiforme. Other symptoms such as hepatitis, cystitis, increased appetite and weight gain, headache, dry mouth, psychomotor impairment, increased bronchial secretions, constipation, increased gastroesophageal reflux, urination dysuria or urinary retention, convulsions, sweating, myalgia, tremor, sleep disturbance, extrapyramidal effects, tinnitus, alopecia, depression, hypotension. The drug should be stopped when detecting the above side effects or other unusual symptoms after taking Asumalife, and promptly inform the treating doctor about the use of Asumalife or immediately go to the nearest medical facility. for prompt treatment.

5. Note the use of Asumalife drug in the subjects

Asumalife should be used with caution in patients with a history of or ongoing seizures, epileptic seizures, idiopathic thrombocytopenic purpura, patients with adrenal insufficiency being treated with corticosteroids. Avoid using Asumalife in children under 6 months of age, as safety studies are still limited. Pregnancy: There are limited data on the adverse effects of Ketotifen fumarate contained in Asumalife in pregnant women. Therefore, only use Asumalife drug on this subject when absolutely necessary. Lactation: Some research indicates that Ketotifen fumarate can pass into breast milk. Therefore, breastfeeding should be discontinued when deciding to use Ketotifen fumarate. Drivers or workers who operate machinery are often less likely to experience side effects such as drowsiness to deep sleep, fatigue, dizziness, dizziness ... after taking Asumalife.

6. Asumalife drug interactions

Interactions with other drugs
Do not suddenly stop using asthma medicines such as Corticosteroids, Xanthin derivatives, β2 agonists, Sodium cromoglycate... when you start using Asumalife. Asumalife increases the sedative effect of central nervous system depressants such as barbiturates, opioid analgesics, muscle relaxants, antiepileptic drugs, tranquilizers, sleeping pills, alcohol... Asumalife increases Antimuscarinic effects of Atropin, tricyclic antidepressants and MAO inhibitors. Asumalife masks the side effects of aminoglycoside antibiotics. Avoid the use of Asumalife and oral antidiabetic drugs, as they may temporarily increase thrombocytopenia. Above is the basic information about the composition, uses, dosage and notes when using Asumalife medicine. Patients and relatives should carefully read the instructions for use of Asumalife medicine and strictly follow the instructions of the doctor or pharmacist to get the best treatment results.
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