This is an automatically translated article.
Article written by BSCK II Nguyen Thu Hoai, Obstetrics Department - Vinmec Times City International Hospital
PAPP-A has many important roles in embryonic development, especially helps in the growth and development of the placenta, controls the development of the fetus by regulating the absorption of amino acids and glucose. of immature cells (through the release of IGF factor), in addition, PAPP-A helps to protect the fetus against the mother's immune system. So is the low concentration of PAPP-A in the Double test worrisome?
From 12-14 weeks of pregnancy, pregnant women need to have morphological ultrasound and Double test to screen for the risk of chromosomal abnormalities. However, in the Double test test, an indicator that plays an important role in assessing the pregnancy progress of a pregnant woman is the PAPP-A index.
What is PAPP-A? It is an abbreviation for Pregnancy Associated Plasma Protein-A (PAPP-A), a large molecular weight glycoprotein produced mainly by the placenta (also partly from the placenta and fetus). PAPP-A has many important roles in embryonic development, especially in the growth and development of the placenta, in controlling fetal development by regulating the absorption of amino acids and glucose by the fetus. immature cells (through the release of IGF factor), in addition, PAPP-A helps to protect the fetus against the mother's immune system.
PAPP-A có vai trò quan trọng trong quá trình phát triển phôi thai
According to an article by Ciobanu A published in Am J Obstet Gynecol 2019, pregnant women with PAPP-A levels below 0.45 MoM have an increased risk of intrauterine growth retardation, labor and delivery. prematurity, stillbirth, and preeclampsia. For pregnant women with low PAPP-A test results, the obstetrician may prescribe low-dose aspirin to prevent these complications from occurring. Women need periodic antenatal check-ups to monitor blood pressure, proteinuria, ultrasound to assess fetal development, and amniotic fluid volume.
With early diagnosis, prevention, and proper planning of pregnancy monitoring, the prognosis can be avoided in 70-75% of cases. So, if you have a low PAPP-A test result, don't worry too much. See your obstetrician for advice and the best treatment and monitoring for your pregnancy.
To protect the health of pregnant women and their babies during pregnancy, Vinmec International General Hospital provides a package of maternity services as a solution to help pregnant women feel secure because of the companionship of the medical team. doctor throughout pregnancy. When choosing Maternity Package, pregnant women can:
The pregnancy process is monitored by a team of highly qualified doctors Regular check-ups, early detection of abnormalities The package pregnancy helps to facilitate convenient for the birthing process Newborns get comprehensive care
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
