The role of AMH hormone in assisted reproduction

This is an automatically translated article.

The article was professionally consulted by Specialist Doctor I Nguyen Thi Man - Department of Obstetrics and Gynecology - Vinmec International General Hospital Da Nang.

The AMH test is the most accurate test to assess the fertility of the ovaries. This test plays a very important role in assisted reproduction.

1. What is AMH?


AMH is an acronym for Anti-mullerian Hormone. This is a hormone secreted directly by the granulosa cells of the ovarian follicle and is directly related to the number of primordial follicles in the ovary. The amount of AMH indicates the number of immature follicles currently in the ovary, also known as the ovarian reserve. Better ovarian reserve means higher fertility of the ovaries and vice versa.
AMH levels do not change with the menstrual cycle, so it can be performed on any day of the menstrual cycle. This is the advantage of the AMH test over the previous FSH test. Therefore, making ovarian fertility testing becomes much more convenient for patients. Previously, tests to evaluate ovarian function (FSH, LH, E2) had to be performed at the beginning of the menstrual cycle (days 2-4).

2. The role of AMH hormone in assisted reproduction


Xét nghiệm AMH đóng vai trò rất quan trọng chẩn đoán và điều trị hiếm muộn
Xét nghiệm AMH đóng vai trò rất quan trọng chẩn đoán và điều trị hiếm muộn

This test plays a very important role in the diagnosis and treatment of infertility, especially before ovarian stimulation and in vitro fertilization.
In the treatment of infertility and infertility, ovarian stimulation is a very important step in order to increase the chances of having many good, quality eggs, increasing the chances of successful fertilization and development from there. increase your chances of getting pregnant. Before conducting ovulation, the doctor needs to test a few indicators to know the reserve function of the ovaries. Based on the results of the AMH concentration test, there are the following cases:
In healthy women and under 38 years of age, normal AMH levels are in the range of 2.0 - 6.8 ng/ml (14.28 - 5). 48.55 pmol/L). AMH levels do not change significantly during the menstrual cycle and decrease with age.

Chỉ số AMH < 1ng/ml được xem là thấp và tiên lượng trong hầu hết các trường hợp là rất khó có thai
Chỉ số AMH < 1ng/ml được xem là thấp và tiên lượng trong hầu hết các trường hợp là rất khó có thai

Low expression of AMH when the AMH index is about 1.0-1.5 ng/ml indicates reduced ovarian reserve, but there is still a chance of pregnancy. An AMH index < 1 ng/ml is considered low and the prognosis in most cases is very difficult. Women with low AMH levels often do not respond well to fertility drugs and must use larger amounts of the drug to successfully induce ovulation. A blood level of AMH > 6.8 ng/mL is common in patients with polycystic ovary syndrome, and if not treated appropriately, it will also make it difficult for the patient to become pregnant. fertility of the ovary and as a basis for selecting methods of egg stimulation or providing advice to couples. In addition, assessment of AMH levels is also useful in women who wish to delay childbirth and plan for future pregnancies. The AMH index began to be used as an indication in assisted reproduction.

Specialist I Nguyen Thi Man is former Head of Obstetrics Department - Tam Tri Da Nang General Hospital, Head of IUI unit (Intrauterine Insemination) - Hoan My Hospital - Da Nang. The doctor has more than 10 years of experience in diagnosing, consulting and treating in the field of Obstetrics and Gynecology such as:
Infertility examination and consultation, implementation of assisted reproductive techniques such as: Ovulation monitoring, intrauterine insemination (IUI) Examination, ultrasound, screening and treatment of gynecological diseases Laparoscopic surgery for ovarian cysts, ectopic pregnancy

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