Repeated miscarriage: What you need to know

This is an automatically translated article.

Repeated miscarriage is a condition in which a woman has two or more spontaneous miscarriages, mostly within the first 12 weeks of pregnancy. Examination, testing to find the cause, and good treatment can increase the odds of a healthy pregnancy by up to 70%.

1. What is a recurrent miscarriage?


Miscarriage is the loss of a pregnancy before the 20th week of pregnancy, or when the new baby weighs less than 500 grams. Repeated miscarriage is when a patient has had 2 or more spontaneous miscarriages.
In fact, spontaneous abortion accounts for 15% of all pregnancies. Many women don't even realize they're pregnant until they miscarry. This is because most pregnancies are miscarried within the first 12 weeks of pregnancy.
The mother has a very high risk of having another miscarriage if she has ever had a miscarriage.

2. Causes of consecutive miscarriages


Rối loạn nhiễm sắc thể và gen di truyền có thể là nguyên nhân gây sảy thai liên tiếp
Rối loạn nhiễm sắc thể và gen di truyền có thể là nguyên nhân gây sảy thai liên tiếp

There are many causes of recurrent miscarriage, in which, the most common causes are:
Immune and hormone abnormalities Chromosome and genetic disorders, severe malformations Abnormalities in structure Anatomy of a woman's uterus. Infection. The cause of the miscarriage is unknown. If miscarriage is less than 12 weeks, 70% of fetuses have chromosomal disorders, severe malformations, infections, and endocrine diseases of the mother.
Miscarriages of more than 12 weeks are often caused by abnormalities in the mother's uterus, pre-eclampsia, eclampsia, infection, maternal endocrine diseases such as diabetes, hypothyroidism, lupus,...
2.1 Any Immune and hormonal abnormalities Immune and hormone abnormalities are a major cause of recurrent miscarriage in women. These abnormalities can stem from abnormalities of the ovum, sperm, or embryo.
Luteal phase deficiency Hypothyroidism: If untreated, hypothyroidism can increase the risk of recurrent miscarriages: miscarriage, premature birth, low birth weight, gestational hypertension. Sugar intolerance: Sugar intolerance is considered a direct cause of recurrent miscarriages and birth defects. Women with diabetes and high HBA1c in the first trimester of pregnancy have a much higher risk of miscarriage and malformations. Increased prolactin: Increased prolactin has been shown to increase the risk of miscarriage for women. 2.2 Chromosomal and genetic disorders, severe malformations In some cases, one parent has small abnormalities in the genome, these abnormalities may not affect the parents, but they do. large to the embryo, fetus and can lead to miscarriage.
High maternal age is one of the causes of increased miscarriage rate due to reduced oocyte quality leading to chromosomal abnormalities. A 40-year-old woman is twice as likely to have a miscarriage than a 20-year-old mother.
2.3 Infections
Some infections can cause birth defects, even miscarriages, such as: Rubella, measles, mumps, cytomegalovirus, gonorrhea, HIV,...
2.4 Abnormalities in pregnancy Anatomy of the uterus A septate uterus increases the risk of miscarriage. Bicornuate uterus, mouse uterus, double uterus Adhesions to the uterus Polyps of the uterus Polyps Submucosal fibroids Cervical cleft (common in second trimester miscarriages). 2.5 Unexplained miscarriage In fact, up to 20% of miscarriages are unexplained. In these cases, the doctor may consider some suitable fertility support measures to help the couple give birth to a normal, healthy baby.
In addition, if the mother smokes, drinks alcohol, uses drugs too much, it will also increase the risk of recurrent miscarriage. Some medications can cause miscarriage. Therefore, during pregnancy, women are not allowed to self-medicate but must follow the doctor's instructions.

Trên thực tế, có đến 20% trong số các trường hợp sảy thai là không rõ nguyên nhân
Trên thực tế, có đến 20% trong số các trường hợp sảy thai là không rõ nguyên nhân

3. What tests should be done for consecutive miscarriages?


Before doing the tests, the doctor will ask the patient and perform a clinical examination of the patient to assess the status of medication, surgery, as well as genetic and genetic abnormalities of both spouses, as well as as family and relatives.
Chromosome testing
Chromosome testing is done for both husband and wife to look for genetic causes of abnormalities. Parents can be healthy carriers of a recessive gene for a certain chromosomal disease. Thus, screening and diagnostic testing for chromosomal disease can help detect these abnormalities that have been passed on to the fetus and caused recurrent miscarriages.
Evaluation of the anatomical structure of the female reproductive organs
For women, the uterus and uterine cavity should be evaluated in detail. There are many tests used to evaluate the uterus, including:
Routine ultrasound Water pump ultrasound Hysterosalpingography - tubal resonance imaging (MRI) or hysteroscopy. Other tests
Tests for genetic abnormalities in blood clotting should also be performed in patients with risk factors such as: surgery, fracture, prolonged immobilization or patients have a family with blood abnormalities. Blood test Semen analysis,... After performing diagnostic tests, the couple will be treated according to the cause. Treatment and close monitoring can increase future survival rates by up to 70%.
At Vinmec International General Hospital, there is a package maternity service as a solution to help pregnant women feel secure because of the companionship of the medical team throughout the pregnancy. When choosing Maternity Package, pregnant women can:
The pregnancy process is monitored by a team of qualified doctors Regular check-up, early detection of abnormalities Maternity package helps to facilitate the process. birthing process Newborns get comprehensive care

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

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