List of 5 types of rabies vaccines circulating in Vietnam

This is an automatically translated article.

Many patients, after being bitten by a dog with rabies symptoms, were extremely worried, afraid, and confused. So when is the best time to get vaccinated against rabies? What vaccines are currently being used in Vietnam?

1. What is rabies? How dangerous?

Rabies is caused by a virus that is transmitted from animals to humans.
There are two clinical forms of rabies:
Insanity. Dumb rabies (polio). Of these, the frenzy is the most common. Rabies usually increases in the summer.
Rabies virus enters the nervous system of mammals. The rabies virus is mainly transmitted from the saliva of rabid animals to humans through bites or scratches on the human body. The closer the dog bite site is to the central nervous system, the faster the victim will develop the disease. 96% of human rabies cases in Southeast Asia are caused by dog ​​bites.

Có hai thể bệnh lâm sàng của bệnh dại
Có hai thể bệnh lâm sàng của bệnh dại

2. What to do if bitten by a dog

If bitten by an animal, especially a dog showing signs of rabies, must immediately perform first aid and take the patient to a medical facility.
The wound should be washed immediately with soap and under running water continuously for about 10-15 minutes. If soap is not available, immediately wash the wound with clean water under running water continuously for 15 minutes. This is the most effective first aid method against rabies. The wound should be thoroughly cleaned with 70% alcohol or alcohol iodide, if available. Immediately bring the patient to a medical facility for treatment as soon as possible. The doctor will base on the condition of the patient as well as the animal that has bitten the person for urgent treatment

Hướng dẫn điều trị sau khi phơi nhiễm theo khuyến cáo của WHO
Hướng dẫn điều trị sau khi phơi nhiễm theo khuyến cáo của WHO

3. 5 types of rabies vaccines are being circulated in Vietnam

Currently, there are 5 rabies vaccines that have been granted circulation registration certificates and have been imported or can be imported into Vietnam (no import license is required), including:
Verorab (made in France). Abhayrab (India). Indirab (India) Rabipur (India). Speeda. 3.1. Verorab vaccine

Vắc xin Verorab
Vắc xin Verorab
Manufacturer: Sanofi Pasteur, France.
Indications
Pre-exposure:
Verorab is indicated for the prophylaxis of rabies in subjects at high risk of exposure such as staff working in laboratories for rabies diagnosis, research and production. These subjects should have diagnostic serology every 6 months. If the antibody level is less than 0.5 UI/ml, a booster injection is required. The following people should be vaccinated against rabies because of the risk of rabies infection: Veterinarians, animal keepers and caregivers, hunters, rangers, abattoirs, cave researchers, stuffed animal maker. People traveling to or moving to an area with animal disease. Post-exposure:
As soon as exposure is confirmed or suspected, vaccination should be initiated immediately to minimize the risk of rabies infection. Rabies vaccination must be done at the Rabies Treatment Center. Treatment should be based on the condition of the animal and the type of wound. Route, Dosage
Intramuscular: with a dose of 0.5ml of the reconstituted vaccine, in adults into the Delta muscle area in the arm, children inject in the front - side of the thigh. Do not inject in the buttocks area. Intradermal injection: with a dose of 0.1ml of reconstituted vaccine (equal to 1/5 of an intramuscular dose) Undesirable effects may be encountered after injection
Reactions at injection site: swelling, pain, redness of the skin. Systemic reactions: Headache, fatigue, shivering, possibly fever. There may be joint pain, muscle pain. Stomach and intestinal disorders. Rarely, anaphylaxis. 3.2. Abhayrab Vaccine Manufacturer: Human Biological Institute Company, India.
Abhayrab vaccine is a purified vero cell rabies vaccine, which works to create active immunity against rabies for both adults and children, after contact or being bitten by a suspected rabies animal.
Indications:
Abhayrab helps create active immunity against rabies virus for both adults and children, for prevention and treatment after exposure (after contact with animals with rabies or suspected rabies). ). Rabies is a deadly disease, so the vaccine has no age limit. Abhayrab can be used by all ages. In addition, it is recommended to vaccinate against rabies Abhayrab for high-risk subjects such as: Veterinarians; medical staff, laboratory staff; people working in forests, zoos; People who often come into contact with animals such as butchers, hunters; People with many pets such as dogs and cats in the house... Route of use:
Abhayrab is indicated for intramuscular injection. Adults injected brachial deltoid muscle. Young children inject on the front side of the thigh. Do not inject into the buttocks area. In some cases, an intradermal injection may be indicated. Inject in the forearm or arm. Undesirable effects:
Abhayrab is a purified vero-cell rabies vaccine, so side effects are usually mild. After injecting Abhayrab, some unwanted effects may occur such as:
At the injection site: Pain, itching at the injection site. The whole body is not common: fever, dizziness, headache... Rare: urticaria, anaphylaxis. 3.3. Indirab Vaccine Manufacturer: Bharat Biotech International Limited, India.
Is a purified inactivated rabies vaccine on Vero cells indicated for prophylaxis and post-exposure treatment of rabies in humans of all ages.

Thành phần lọ vắc xin đông khô Indirab
Thành phần lọ vắc xin đông khô Indirab
3.4. Rabipur Manufacturer: Chiron Behring Vaccines Pvt. Ltd., India.
Generic name: PCEC rabies vaccine
Rabipur (chicken embryo purified cell rabies vaccine), human rabies vaccine, is a sterile lyophilized vaccine obtained by growing inactivated Flury LEP strain virus in original chicken fibroblast medium. The lyophilized vaccine meets WHO requirements for safety and efficacy.
Rabipur for intramuscular administration, the vaccine does not contain pyrogen as well as excipients and preservatives.
3.5. Speeda Vaccine Manufacturer: Liaoning Chengda Biotechnology, China
This vaccine is still being produced and supplied to the markets of countries including Vietnam.
Moreover, this is not the vaccine in the scandal in China before the media reported, so the patient can rest assured when receiving treatment.
Vinmec International General Hospital is currently providing a Package Immunization Program with a variety of vaccines for different audiences, from infants, young children, adults, women before and during pregnant.
Particularly in December 2019, Vinmec will give you free newborn Hepatitis B Vaccine (immunization right after birth) for your baby when you sign up for a Package Immunization Package for children aged 0-1 or 0-2 year old .

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

Share
Patients Stories