Embryo culture system and quality management program at IVF Vinmec

This is an automatically translated article.

The article is written by MSc.Nguyen Thi Nhu Trang and IVF Specialist. Tran Hue Tran - Reproductive Support Center - Vinmec Times City International General Hospital.
The role of the laboratory system accounts for 70% of the success rate of an IVF center. Meanwhile, the quality of the lab depends on ensuring the embryo culture system is working properly. The basic embryo culture system includes Lab quality, embryo culture cabinet system and Lab quality management system.

1. Quality of Lab

Currently, building a clean room is a top concern before building an IVF lab. The clean room is designed with a positive pressure system and a modern multi-layer filter, which strictly controls the indicators of dust, bacteria and the concentration of volatile organic compounds (VOCs).
Lab system at IVF Vinmec is built to meet international standards of cleanliness with the most rigorous standards. This proves that Vinmec always focuses on improving quality, giving customers the best services and results.

2. System of incubators

Most of the time in the culture process, gametes and embryos are placed inside the incubator, so it is considered the most important device. At Vinmec today, we have the most modern incubator system, which is being applied at major IVF centers around the world, ensuring embryos are developed with the same conditions as in the mother's womb.
Tri-gas incubator: is a large incubator, with the advantage of creating a uniform environment in the cabinet, but it is easy to lose gas and heat when opening the cabinet and the recovery time is long. Single-compartment incubator (benchtop/mini-incubator): is a new generation incubator with outstanding advantages and features, overcoming the disadvantages of large incubators. The single-compartment incubator achieves optimum stability and stability due to its many separate chambers, which ensure clean and sterile conditions, and the ability to control and calibrate the desired temperature, CO2 and O2 concentrations.

Time-lapse incubator: It is a multi-compartment culture cabinet with integrated microscope and automatic camera in each compartment. This type of cabinet is modern and has many advantages today. In addition to combining the advantages of a multi-compartment culture cabinet, the cabinet is equipped with a camera to monitor and take pictures of embryos continuously (Time-lapse), which helps embryologists easily record information of gametes and embryos, quickly detects division abnormalities that may not be detected in conventional culture incubators.

3. Quality Management Program

To ensure a smooth and accurate operation of the IVF cycle, Vinmec IVF Center has applied the world's most modern science and technology in Lab quality management with two equipment: DATAssure and RI Witness system to minimize errors and risks in IVF Lab..
RI Witness: is an electronic witness system, helps to identify specialized patients in IVF, using tools Gametes and embryos containing a radio frequency identification (RFID) chip. The two main advantages of the RI Witness system include: Biological samples such as ovum, sperm and embryo are guaranteed to be from the exact same couple. The system will continuously alarm when any incompatible models appear. RI Witness helps to record, track and aggregate data for all operations in the extremely complex IVF process. Equipped with the RI Witness system, patients can participate in the control of confusion, avoid risks during the treatment process, and reduce pressure on doctors and embryologists.

RI witness system helps to minimize errors and risks in IVF concentrations of volatile organic compounds (VOCs) to temperature parameters, CO2 concentrations of all embryo culture cabinets. In particular, the DATAssure system also has probes that monitor the temperature of the embryo storage tank, ensuring that the embryos are preserved in the most optimal deep cold conditions. If there are any changes or non-optimal conditions, the system will alarm, and send email and call to notify the embryologist for quick and timely handling. Vinmec IVF Center is one of the first centers in Vietnam to apply modern technology in Lab quality management to help improve the efficiency of an IVF cycle, confidently bring the best services. for infertile couples, helping them have healthy children.

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