Effect of embryo culture on IVF results

This is an automatically translated article.

The article is professionally consulted by Master, Doctor Nguyen Thi Cam Van - Reproductive Support Center - Vinmec Times City International General Hospital.

1. Meaning and role of embryo culture

Embryo culture creates conditions for infertile and infertile people to have a chance to have children from the father's sperm and mother's eggs. In the case of surrogacy, the embryo is placed and developed in the uterus of the surrogate whose child is not genetically related to the surrogate.
In vitro fertilization embryo culture is the stage after the egg is successfully fertilized in vitro. The egg then develops into an embryo in the same nutritional environment in the mother's body. Embryos are cultured before being placed in the mother's uterus which increases the chances of developing into a fetus depending on the degree of division and when deciding to end the culture.
Cultivation of embryos to blastocyst stage takes more time than conventional culture about 2-3 days. Cultivation to this stage helps in basic embryo screening before transfer to the uterus because if the embryo has abnormal chromosomes, it will not be able to develop to the blastocyst stage.

When a woman has an egg aspiration, uterine contractions will occur, the symptoms usually last 2-3 days and then gradually subside. If the embryo culture takes place until the 5th - 6th day, the transferred embryo will be safer, avoiding being pushed out.

2. Embryo culture process

Embryo culture is essentially an important step in the IVF process. The process begins when the wife's egg is aspirated and fertilized by the husband's sperm. After the egg is fertilized, it is cultured to develop into an embryo, which is able to exist independently in the woman's uterus.
The process of embryo culture will take place in 5 to 6 days:
After fertilization, the eggs will form embryos and are cultured in a special environment that creates the most optimal conditions for embryo development. The culture medium was changed sequentially from the start of culture to the formation of the blastocyst (the embryo has divided into 60 to 200 cells). CO2 concentration, temperature, humidity, and light intensity are also adjusted according to each stage of embryo development. The embryo culture goes through the stages of observation, analysis and evaluation by experts before selecting a well-developed embryo to put into the woman's uterus. It is possible to transfer embryos at the stage of embryo division, when the embryo has about 6-8 cells.

Or, embryos can be cultured to the blastocyst stage to transfer to the mother's uterus. By observing the embryo's morphology under an inverted microscope and a specialized camera set, along with professional experience, experts can evaluate the morphology and development stage of the embryo. Thereby predicting the abnormal development of embryos of poor quality, which is one of the main causes of implantation failure, recurrent miscarriage...
In vitro fertilization embryo culture should be carried out. in a special culture medium. Along with the process of culturing embryos needs to be done accurately and meticulously to ensure a high success rate when being inserted into the woman's body.
Customers can come to the Center for Reproductive Support - Vinmec International General Hospital. This is the leading center in Vietnam, which has developed and applied a comprehensive medical examination and treatment process, combining both gynecology and obstetrics and gynecology to provide the optimal method for each patient's case.

Advantages when customers choose Vinmec fertility center:
Equipped with modern equipment, clean air system according to international standards to ensure lab quality, single cabinet system to optimize quality embryos, improving the success rate for each cycle of IVF. Implement most advanced assisted reproductive techniques in the world: ICSI (injection of sperm into the oocyte cytoplasm); support embryo escape membrane; Reproductive reserve: embryo freezing, sperm freezing, oocyte freezing to help customers take the initiative in giving birth at will, transferring embryos on day 5, minimizing pregnancy; male infertility techniques (PESA, MESA, TEFNA, TESE) Besides advanced reproductive support methods, a team of excellent doctors in the country and the world, with prestige and long-term experience in the field of infertility . Master. Doctor. Nguyen Thi Cam Van has experience and strength in performing specialized techniques on assisted reproduction in the IVF lab. Before being an IVF lab doctor at the Reproductive Support Center, Vinmec Times City International Hospital, he had obtained foreign training certificates such as: Certificate of Advanced Reproductive Technology at IVF GangNam Cha, Korea, Certificate of Quality Management in IVF lab at Origio lab, Denmark.
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Fertility assessment for husband and wife at Vinmec: What tests are needed? In what cases is intrauterine insemination (IUI) indicated? What is genetic screening before embryo transfer? Why does it need to be done?