"Decoding" AMH and fertility related

This is an automatically translated article.

As a hormone secreted directly from the granulosa cells of the ovarian follicle, AMH is an important indicator of ovarian reserve as well as a woman's fertility. Fluctuations in this index can directly affect your chances of conceiving.

What is the AMH Index? How much is normal? How much is abnormal?


AMH (abbreviated as Anti - Mullerian Hormone) is a hormone secreted directly from the granulosa cells of the ovarian follicle, indicating the number of immature follicles present in a woman's ovaries. This is an indicator of ovarian reserve in a woman.
Characteristics of the AMH index :
The index peaks at the age of 25 and tends to decrease with age; Not fluctuating even during the menstrual cycle; As a measure of ovarian reserve, predicting a woman's fertility now and in the future.

How is AMH related to fertility? What does the AMH test mean in IVF?


In women, the better the ovarian reserve, the better the fertility. The AMH low ovarian reserve test is an important step in assessing a woman's fertility, especially for those who intend to undergo IVF.

Xét nghiệm AMH đánh giá khả năng sinh sản của phụ nữ
Xét nghiệm AMH đánh giá khả năng sinh sản của phụ nữ

Although AMH levels do not change with the menstrual cycle, they are still affected by age or pathological factors, lifestyle, and stress.
In women who are healthy and <38 years old, normal AMH ranges from 1.25 to 4.74 ng/ml.
An AMH reading of 1.0-1.25 ng/ml represents a decline in ovarian reserve, but there is still a chance of pregnancy (despite difficulty). A low AMH index: <1 ng/ml means that in most cases the prognosis is very difficult to get pregnant. The extremely low AMH index (<0.5ng/ml) evaluates the low ovarian reserve, the two ovaries have shrunk and cannot be found on ultrasound, the ability to conceive is difficult. In these cases, there are often indications to ask for eggs to get pregnant. If the AMH index is too high and too high (>10 ng/ml), which often occurs in women with polycystic ovaries, the customer has the opportunity to obtain many oocytes, many embryos, but the customer also has to face risks. ovarian hyperstimulation, and reduced effectiveness of IVF. In general, AMH levels that are too low or too high can put patients at a disadvantage during IVF.

Chỉ số AMH ảnh hưởng đến quá trình thụ tinh ống nghiệm
Chỉ số AMH ảnh hưởng đến quá trình thụ tinh ống nghiệm
At the Center for Reproductive Support (Vinmec Times City International Hospital), couples will receive a comprehensive examination and assessment of health problems before an IVF is indicated. Couples will undergo the first step of a reproductive health checkup (male, female). For women, AMH will be measured as well as other tests to assess fertility.
The AMH index test can be performed by 2 methods: manual and automatic. The automatic method has many advantages such as fast result return time, accuracy, high reliability, less error related to operator, better data management. Vinmec currently uses an automatic AMH test method using the most modern testing machine system, Cobas 8000 - E801 by masters and doctors specializing in immunochemistry, in a laboratory that meets quality management standards. ISO 15189.
After AMH test and reproductive health examination, if there is an indication to perform IVF, it will undergo ovarian stimulation - Oocyte aspiration/embryogenesis - Embryo transfer. Couples with failed embryo transfer will be assigned testing to find the cause of failure.
Vinmec is one of the prestigious units in the field of assisted reproduction in Vietnam, with a team of experienced doctors, trained in developed countries. Vinmec's system of equipment, facilities, laboratories, and embryo culture cabinets is the most modern in the region, helping the success rate of IVF to be equivalent to that of developed countries.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

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