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Praxilen belongs to the group of brain activating drugs and peripheral vasodilators. With the main ingredient is Naftidrofuryl oxalate, Praxilen is used to treat claudication symptoms of lower extremity artery occlusion (stage 2), dementia in the elderly, cognitive loss (except Alzheimer's disease). ).1. What is Praxylene?
Praxilen medicine has the main ingredient Naftidrofuryl hydrogen oxalate 200mg (equivalent to Naftidrofuryl 162mg). Praxilen is indicated for use in the following cases:Cognitive decline, dementia caused by cerebral blood vessels; Chronic obstructive arteritis of the lower extremities (stage 2), claudication; After cerebral ischemic stroke; Support treatment of Raynaud's syndrome.
2. Instructions on how to take Praxilen
2.1. How to use
Praxilen is prepared in the form of 200mg film-coated tablets, absorbed orally. The drug should be taken with meals. Swallow the tablet whole (do not chew, bite or crush) and drink it with a large glass of water.
Note: The content of Oxalate in 1 tablet of 200mg is 38mg. Therefore, it is advisable to drink enough fluids during treatment to maintain adequate urine output. If you take Praxylene before going to bed without drinking water, it can cause local esophagitis. Therefore, always take Praxilen 200mg with a large glass of water.
2.2. Dosage
Treatment of lower extremity arteritis & cerebrovascular accident: Take 3 tablets/day, divided into 3 times (corresponding to 600mg Naftidrofuryl oxalate/day); Treatment of dementia in elderly people, cognitive impairment, after ischemic stroke, Raynaud's syndrome: Take 2 tablets/day, divided into 2 times (corresponding to 300-400mg Naftidrofuryl oxalate/day) ). Note:Praxilen should only be used as an adjunct to other treatments (eg control of cardiovascular risk factors, regular exercise/sports, smoking cessation); After about 6 months of treatment, the patient should reassess the response to treatment and consider whether to continue if the condition does not improve; Praxilen is mainly used for the elderly, so there is no need to adjust the dose for this group of subjects.
3. Side effects of the drug Praxilen
When using Praxilen, users may experience some unwanted effects as follows:Uncommon side effects: Digestive disorders (diarrhea, nausea, vomiting, epigastric pain, vomiting) ; changes in urine composition, skin rash, oral mucosal ulcers; Rare side effects: Calcium oxalate kidney stones, liver damage. In cases of suspected liver damage, the patient should have transaminase levels checked. The drug should be discontinued if signs suggestive of liver damage occur and if a (even moderate) elevation of transaminase levels is observed.
4. Notes when taking the drug Praxilen
Before using Praxilen, users should carefully read the instructions for use and refer to the information below.Contraindicated using Praxilen 200mg for the following cases:
People with hypersensitivity to Naftidrofuryl or any of its ingredients; Known hyperoxaluria; There is a history of recurrent calcium kidney stones; Congenital galactosemia; Glucose - galactose malabsorption syndrome; Lack of lactase; Children. Other notes:
Praxilen has no effect on lowering blood pressure, so it is not an antihypertensive drug; Naftidrofuryl does not affect the user's ability to drive or use machines. Can be safely used; Praxilen is mainly used in the elderly who are no longer able to become pregnant or breast-feeding. Due to the lack of relevant clinical data, experts do not recommend this drug during pregnancy and lactation.
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