Acute genital ulcer (Lipschutz ulcer): Manifestations and treatment

This is an automatically translated article.

The article was professionally consulted with Doctor Phan Diem Doan Ngoc - Department of Obstetrics and Gynecology, Vinmec Central Park International General Hospital.
Lipschutz ulcer is a rare, non-sexually transmitted disease, but is easily confused with other sexually transmitted diseases because of its similar symptoms.

1. What is an acute genital ulcer (Lipschutz ulcer)?

Acute genital ulcer or Lipschutz ulcer is an acute vulvar ulcer characterized by painful genital sores accompanied by fever and swollen lymph nodes. Rare disease, unknown mechanism of disease, mainly in girls who have not had sex (virgins). Acute genital ulcers are not sexually transmitted but are easily confused with sexually transmitted diseases.
The disease was first described in 1912 by Benjamin lipschutz through the report of an acute clinical case characterized by the sudden appearance of painful genital ulcers, fever, and lymphadenopathy occurring mainly in children. adolescent girls and virgins.

2. Manifestations of acute genital ulcers

Acute genital ulceration presents as single or multiple shallow ulcers with well-defined, sharp contours, overlaid with gray-brown pseudomembranous or scaly exudates, possibly with red halo or edematous periphery. In addition, there may be secondary erythema and edema. Usually, ulcers occur on the edges of the labia minora, but they are also found on the labia majora, perineum, and in the lower vagina.
The “Kissing” ulcer is common on the surface opposite the previous lesion. The sizes of the ulcers are variable and the lesions are larger than 1 cm. Many patients may also have signs such as fever, body fatigue, mouth ulcers.

Hình ảnh loét âm hộ cấp tính ở phụ nữ
Hình ảnh loét âm hộ cấp tính ở phụ nữ

3. Treatment of acute genital ulcers

The goals of treatment are to help relieve pain, heal wounds, and prevent scarring.
Local treatment: Clean the spot Clean the lesion: apply moist gauze, Vaseline gauze. Use antibiotic cream, cream with local anesthetic effect to fight infection and relieve pain: fucidic acid, 2% lidocaine gel or corticosteroid ointment for 7-10 days. The use of intralesional corticosteroids can also be beneficial. Systemic treatment: Pain relief is important in disease treatment. Non-steroid anti-inflammatory pain relievers can be used: paracetamol, acetaminophen..... pain relievers that cause drowsiness. Use of systemic antibiotics to prevent superinfection Systemic corticosteroids are indicated if the patient does not respond to topical agents.

Vệ sinh sạch tổn thương vùng kín và sử dụng kem kháng sinh theo chỉ định của bác sĩ
Vệ sinh sạch tổn thương vùng kín và sử dụng kem kháng sinh theo chỉ định của bác sĩ
In general, the disease has a good prognosis if it is treated well for about 1 week. The ulcer will relieve pain and appear granular tissue. According to many reports, the ulcer usually heals within 16-21 days and most often the disease does not recur. After ulcer healing, annual follow-up is recommended for subsequent systemic disorders (Crohn's disease, Behcet's disease).
If the patient is diagnosed with an acute genital ulcer, the patient and family should not be too worried because the disease is not sexually transmitted and the ulcer can be completely cured, leaving no sequelae.

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References: ncbi.nlm.nih.gov
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